In-vitro activity of active ingredients of disinfectants against drug-resistant fungi

Juli 2019
R. Stauf, Daniel Todt, Eike Steinmann, Peter Michael Rath, Henrik Gabriel, Jochen Steinmann, Florian Brill
Bibliografische Daten 
Journal of Hospital Infection

The biocidal activities of peracetic acid and ethanol were tested against nine clinical fungal isolates and four reference strains. Ethanol was active (≥4.0 log10 reduction) against yeasts at a concentration of 50% v/v and against moulds at 80% v/v. Exposure times in both cases were 1 min. Peracetic acid was active as a 0.25% solution against yeasts and as a 0.5% solution against moulds; exposure times in both cases were 5 min. Compared with the reference strains, clinical isolates, including multi-drug-resistant strains, showed similar or higher sensitivity to the active ingredients of disinfectants in vitro.